β3-Adrenoceptor Stimulation on Top of β1-Adrenoceptor Blockade
نویسندگان
چکیده
منابع مشابه
Blockade of β2-adrenoceptor, rather than β1-adrenoceptor, deteriorates cardiac anaphylaxis in isolated blood-perfused rat hearts.
BACKGROUND Cardiac anaphylaxis is one of the features of anaphylactic hypotension. Patients treated with propranolol, a nonselective β-adrenoceptor (AR) antagonist, develop severe anaphylaxis, but the mechanism remains unknown. Under examination were the effects of β1- and β2-AR antagonist on anaphylaxis-induced coronary vasoconstriction and cardiac dysfunction in isolated blood-perfused rat he...
متن کاملBeta-adrenoceptor blockade and anesthesia
A potential for impaired cardiovascular performance among anesthetized patients due to preoperative treatment with propranolol was considered based on clinical observation of sudden, irretractable cardiac failure in five patients. As a result, a recommendation to terminate beta-adrenoceptor therapy prior to general anesthesia was advanced. During the ensuing decade many clinical researchers sou...
متن کاملβ1-Adrenoceptor blocker aggravated ventricular arrhythmia.
OBJECTIVES To assess the impact of β1 -adrenoceptor blockers (β1 -blocker) and isoprenaline on the incidence of idiopathic repetitive ventricular arrhythmia that apparently decreases with preprocedural anxiety. METHODS From January 2010 to July 2012, six patients were identified who had idiopathic ventricular arrhythmias that apparently decreased (by greater than 90%) with preprocedural anxie...
متن کاملInvestigation of adrenoceptor genes (β2 & β3) in women with polycystic ovary syndrome
Background: Genetic polymorphism is responsible for variations and individual differences. Polymorphism is a major factor of complex diseases with unknown etiology and cancer. Inconsistency in the symptoms of polycystic ovary syndrome (monthly disorder, hirsutism, obesity, diabetes, infertility) is one of the major pathological complications of this syndrome. The present study was conducted to ...
متن کاملDynamics of 3-adrenoceptor blockade with cetamolol
1 Cetamolol is a new 3-adrenoceptor blocking agent shown in animals to have moderate PI -adrenoceptor selectivity and partial agonist activity. 2 In healthy normal volunteers, PI -adrenoceptor blockade was measured as the reduction of exercise-induced tachycardia, systolic blood pressure, and double product at 2, 8, and 24 h after a single oral dose of 10, 25, and 50 mg cetamolol. 3 P1-adrenoce...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 2009
ISSN: 0735-1097
DOI: 10.1016/j.jacc.2009.01.048